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Insurance coverage scenarios

Here are some potential scenarios for insurance coverage that may apply to your patient’s ability to obtain Synagis at a lower out-of-pocket (OOP) cost.

Health Plan


  • Patient pays portion of monthly premium through employer (deducted from their pay)
  • Employer also contributes to premium
  • Patient will likely be responsible for paying a copay or coinsurance depending on their insurance coverage

Health Insurance Marketplaces (Exchanges)


  • Patient buys policy through federal, state, or partnership marketplace (depending on the state) and pays monthly premium
  • Patient will likely be responsible for paying a copay or coinsurance depending on their insurance coverage

Medicaid (Fee-for-Service or Managed Medicaid)


  • Patient pays lower premiums than commercial members or may pay a zero premium
  • Patient may have higher OOP costs for Synagis

Uninsured/Not Covered


  • All expenses are self-pay
  • If a patient is without prescription coverage or can’t afford their medication, AstraZeneca may be able to help

Important Safety Information

Synagis® (palivizumab) is indicated for the prevention of serious lower respiratory tract disease caused by respiratory syncytial virus (RSV) in children at high risk of RSV disease. Safety and efficacy were established in children with bronchopulmonary dysplasia (BPD), infants with a history of premature birth (≤35 weeks gestational age), and children with hemodynamically significant congenital heart disease (CHD). The recommended dose of Synagis is 15 mg/kg of body weight given monthly by intramuscular injection. The first dose of Synagis should be administered prior to commencement of the RSV season and the remaining doses should be administered monthly throughout the RSV season. Children who develop an RSV infection should continue to receive monthly doses throughout the RSV season.

The efficacy of Synagis at doses less than 15 mg/kg, or of dosing less frequently than monthly throughout the RSV season, has not been established.

Synagis is contraindicated in children who have had a previous significant hypersensitivity reaction to Synagis. Cases of anaphylaxis and anaphylactic shock, including fatal cases, have been reported following initial exposure or re-exposure to Synagis. Other acute hypersensitivity reactions, which may be severe, have also been reported on initial exposure or re-exposure to Synagis. The relationship between these reactions and the development of antibodies to Synagis is unknown. If a significant hypersensitivity reaction occurs with Synagis, its use should be permanently discontinued. If a mild hypersensitivity reaction occurs, clinical judgment should be used regarding cautious readministration of Synagis. As with any intramuscular injection, Synagis should be given with caution to children with thrombocytopenia or any coagulation disorder. Palivizumab may interfere with immunological-based RSV diagnostic tests, such as some antigen detection-based assays.

Adverse reactions occurring greater than or equal to 10% and at least 1% more frequently than placebo are fever and rash. In post-marketing reports, cases of severe thrombocytopenia (platelet count <50,000/microliter) and injection site reactions have been reported.

Please see full Prescribing Information for Synagis, including Patient Information.