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What is Severe RSV Disease?

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Take the Risk Assessment now.
Then, talk to your pediatrician about the results.

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RSV is a virus that infects the lungs

  • RSV or respiratory syncytial [sin-sish-uhl] virus is a contagious virus that may infect a child's lungs and breathing passages
  • Most children will catch RSV by the age of 2 years
  • RSV spreads rapidly among children. While most will recover in 1 to 2 weeks, infants and children can continue to spread the virus for 1 to 3 weeks, even after recovery

Most children recover from the disease in a week or two, but in preterm infants (≤35 wGA) or those with certain heart or lung problems, RSV can lead to serious lung infection and hospitalization

RSV Season

  • RSV is present year-round but its activity typically goes up in the fall, peaks in the winter, and goes down in early spring. The exact timing of RSV season varies by location.

How severe RSV disease affects the lungs

Lung Structure and Capacity

Click on the buttons below to see estimates of premature
lung development compared to full term.

Full-term lungs

  • Lung volume of preterm infants born at 34 weeks GA is only about half of the lung volume seen in full-term infants
  • A preterm infant’s airways are smaller and narrower than a full-term baby's airways

Even as preterm infants start to look healthy and strong, they remain at high risk for severe RSV disease, in part due to underdeveloped lungs.

Is your baby at high risk?
Take the Risk Assessment now.
Then, talk to your pediatrician about the results.

Take the Risk
Assessment now >

Important Safety Information

Who should not receive SYNAGIS?

Children should not receive SYNAGIS if they have ever had a severe allergic reaction to it. Signs and symptoms of a severe allergic reaction could include itchy rash; swelling of the face; difficulty swallowing; difficulty breathing; bluish color of the skin; muscle weakness or floppiness; and/or unresponsiveness. If your child has any of these signs or symptoms of a severe allergic reaction after getting SYNAGIS, call your child’s healthcare provider or get medical help right away.

How is SYNAGIS given?

SYNAGIS is given as a monthly injection, usually in the thigh (leg) muscle, by your child’s healthcare provider. If your child has a problem with bleeding or bruises easily, an injection could cause a problem. Your child should receive their first injection of SYNAGIS before the RSV season starts, to help protect them before RSV becomes active. RSV season is usually fall through spring, but it may begin earlier or last longer in certain areas. When RSV is most active, your child will need to receive injections of SYNAGIS every 28-30 days to help protect them from severe RSV disease for about a month. Your child should continue to receive monthly injections of SYNAGIS until the end of RSV season. Your child may still get severe RSV disease after receiving SYNAGIS. If your child has an RSV infection, they should continue to get their monthly injections throughout the RSV season to help prevent severe disease from new RSV infections.

The effectiveness of injections of SYNAGIS given less than monthly throughout the RSV season has not been established.

What are the possible side effects of SYNAGIS?

Serious side effects include severe allergic reactions, which may happen after any injection of SYNAGIS and may be life-threatening or cause death. Call your child’s healthcare provider or get medical help right away if your child has any of the signs or symptoms of a serious allergic reaction. See “Who should not receive SYNAGIS?” for more information.

Common side effects of SYNAGIS include fever and rash.

These are not all the possible side effects of SYNAGIS.

APPROVED USE

SYNAGIS is a prescription medication that is used to help prevent a serious lung disease caused by respiratory syncytial virus (RSV) in children:

  • born prematurely (at or before 35 weeks) and who are 6 months of age or less at the beginning of RSV season
  • who have a chronic lung condition called bronchopulmonary dysplasia (BPD), that needed medical treatment within the last 6 months, and who are 24 months of age or less at the beginning of RSV season
  • born with certain types of heart disease and who are 24 months of age or less at the beginning of RSV season

It is not known if SYNAGIS is safe and effective:

  • to treat the symptoms of RSV in a child who already has RSV. SYNAGIS is used to help prevent RSV disease
  • in children who are older than 24 months of age at the start of dosing

Please see accompanying full Prescribing Information for SYNAGIS, including Patient Information.